宜蘭大學 生物技術與動物科學系

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 賴裕順
專任教師
姓名 賴裕順
聯絡電話 03-9357400-7624, 7628
電子郵件 yslai@niu.edu.tw
職稱 教授
授課領域 免疫學、生物學、分子生物學
研究專長 抗體工程、腫瘤轉移機制分子研究
必修
  1. 分子生物學  
  2. 生物學  
  3. 免疫學  
論文名稱 年度
30. S-L Hu(宜大), C-J Liou, Y-H Cheng, J-C Yiu, P P Chiou*, Yu-Shen Lai (賴裕順)* (2015). Development and characterization of two monoclonal antibodies against grouper iridovirus 55L and 97L proteins. Journal of Fish Diseases 38, 249-258. IF=2.056, 13/133(9.7%) Veterinary Sciences 2015
29. Y-S Chiu(宜大), Y-H Cheng, S-W Lin, T-S Chang, C-J Liou, Yu-Shen Lai (賴裕順)* (2015). Bupivacaine induces apoptosis through caspase-dependent and -independent pathways in canine mammary tumor cells. Research in Veterinary Science 100:232-238. IF=1.409, 34/133(25.5%) Veterinary Sciences. 2015
28. A-C Lin(宜大), C-W Liao, S-W Lin, C-Y Huang, C-J Liou, Yu-Shen Lai (賴裕順)* (2015). Canine heat shock protein 27 promotes proliferation, migration, and doxorubicin resistance in the canine cell line DTK-F. The Veterinary Journal 205:254-262 IF=1.755, 22/133(16.5%) Veterinary Sciences. 2015
27. Z-Y Chen(宜大), P P Chiou, C-J Liou, Yu-Shen Lai (賴裕順)* (2015). Development and application of a monoclonal antibody against a putative myristoylated membrane protein encoded by grouper iridovirus 59L gene. Diseases of Aquatic Organisms 113:215-226. IF=1.752, 23/133(17.2%) Veterinary Sciences. 2015
26. Z-Y Chen(宜大), W-Y Hsieh, Yu-Shen Lai (賴裕順)* (2015). Identification and characterization of a late gene of grouper iridovirus 61L and antibody production against the protein encoded by it. Journal of Fish Biology 87, 386-399. IF=1.658, 19/50(38%) Fisheries 2015
25. Chun-Yi He, Su-Der Chen*, Want-Ju Lu, Hung-Cheng Wang, Yung-Chung Chang, Yeong-Hsiang Cheng, Yu-Shen Lai (賴裕順). Effect of Ethanol Extracts from Hericium erinaceum Solid-State Fermented Wheat on Nerve Cells Growth. Hans Journal of Food and Nutrition Science 食品与营养科学, 2015, 4, 1-10 (fully text) 2015
24. H-Y Lin(宜大), C-F Cheng, P P Chiou, C-J Liou, J-C Yiu, Yu-Shen Lai (賴裕順)* (2015). Identification and characterization of a late gene encoded by grouper iridovirus 2L (GIV-2L). Journal of Fish Diseases 38, 881-890. IF=2.056, 13/133(9.7%) Veterinary Sciences 2015
23. Z-Y Chen(宜大), P P Chiou, C-J Liou, Yu-Shen Lai (賴裕順)* (2015). Production and characterization of a monoclonal antibody against a late gene encoded by grouper iridovirus 64L. Journal of Fish Diseases. Epub ahead of print. IF=2.056, 13/133(9.7%) Veterinary Sciences 2015
22. H-Y Lin(宜大), C-J Liou, Y-H Cheng, H-C Hsu, J-C Yiu, P P Chiou, Yu-Shen Lai (賴裕順)* (2014). Development and application of a monoclonal antibody against grouper iridovirus (GIV) major capsid protein. Journal of Virological Methods 205:31-37. IF=1.781, 93/162(68%) Biotechnology & Applied Microbiology 2014
21. Y-L Hsiao(宜大), T-Z Hsieh, C-J Liou, Y-H Cheng, C-T Lin, C-Y Chang*, Yu-Shen Lai (賴裕順)* (2014). Characterization of protein marker expression, tumorigenicity, and doxorubicin chemoresistance in two new canine mammary tumor cell lines. BMC Veterinary Research 10:229. IF=1.777, 21/133(15.7%) Veterinary Sciences 2014
20. Ming-Wei Lu, Fang-Huar Ngou, Yung-Mei Chao, Yu-Shen Lai (賴裕順), Nai-Yu Chen, Fan-Yao Lee and Pinwen P Chiou (2012). Transcriptome characterization and gene expression of Epinephelus spp in endoplasmic reticulum stress-related pathway during betanodavirus infection in vitro. BMC Genomics 2012, 13:651 (SCI). 2012
19. Sui-Wen Lin, Jian-Jhih Huang, Yu-Shen Lai* (賴裕順) (2012). A study of adenosine-mediated inhibition the replication of iridovirus in grouper kidney cells. Journal of Cardinal Tien College of Healthcare & Management. 10.15-24 (non-SCI). 2012
18. Phuc H. Pham, Yu-Shen Lai (賴裕順), Frank Fang-Yao Lee, Niels C. Bols, Pinwen P. Chiou (2012). Differential viral propagation and induction of apoptosis by grouper iridovirus (GIV) in cell lines from three non-host species. Virus Research Jul;167(1):16-25 (SCI). 2012
17. Chi-Yao Chang, Pinwen Peter Chiou, Wei-Jung Chen, Yu-Hui Li, Jinn-Chin Yiu, Yeong-Hsiang Cheng, SU-Der Chen, Chung-Tien Lin, Yu-Shen Lai* (賴裕順) (2010). Assessment of the tumorigenesis and drug susceptibility of three new canine mammary tumor cell lines. Research in Veterinary Science 88, 285-293 (SCI). 2010
16. Ta-Chih Cheng, Yu-Shen Lai (賴裕順), I-Yuan Lin, Chun-Pei Wu, Chi-Lin Chang, Chi-In Chen, Mao-Sheng Su (2010). Establishment, characterization, virus susceptibility and transfection of cell lines from cobia Rachycentron canadum (L.), brain and fin. Journal of Fish Diseases 33(2), 161-169 (SCI). 2010
15. Jinn-Chin Yiu, Cheng-Wei Liu, Denise Yi-Tan Fang, Yu-Shen Lai (賴裕順) (2009). Waterlogging tolerance of Welsh onion (Allium fistulosum L.) enhanced by exogenous spermidine and spermine. Plant Physiology and Biochemistry 47, 710-716. (SCI) 2009
14. Pinwen Peter Chiou., Yen-Chun Chen., Yu-Shen Lai1,* (賴裕順) (2009). Caspase-dependent induction of apoptosis in barramundi, Lates calcarifer (Bloch), muscle cells by grouper iridovirus. Journal of Fish Diseases 32(12), 997-1005(SCI). 2009
13. Su-Der Chen., Shiow- Yun Lin., Yu-Shen Lai (賴裕順)., Yeong-Hsiang Cheng (2008). Effect of Cordyceps sinensis adlay fermentative products on antioxidant activities and macrophage functions. Taiwanese Journal of Aricultural Chemistry and Food Science 46(6), 223-233. (non-SCI) 2009
12. Yu-Shen Lai1,* (賴裕順)., Pinwen Peter Chiou., Wei-Jung Chen., Yen-Chun Chen., Chin-Wen Chen., I-Shu Chiu., Su-Der Chen., Yeong-Hsiang Cheng., Chi-Yao Chang (2008). Characterization of Apoptosis Induced by Grouper Iridovirus in Two Newly Established Cell Lines from Barramundi (Lates calcarifer). Journal of Fish Diseases 31, 825–834. (SCI). 2008
11. Jinn-Chin Yiu., Menq-Jiau Tseng., Chiou-Ying Yang., Cheng-Wei Liu., Yu-Shen Lai(賴裕順)., Chun-Teh Kuo., Hsin-Hsuan Liu (2008). Transgenic rice expresses an antigenic lipoprotein of Neisseria gonorrhoeae. Journal of the Science of Food and Agriculture 88, 1603-1613. (SCI). 2008
10. Jinn-Chin Yiu., Cheng-Wei Liu., Chun-Teh Kuo., Menq-Jiau Tseng., Yu-Shen Lai(賴裕順)., Wan-Jun Lai (2008). Changes in antioxidant properties and their relationship to paclobutrazol-induced flooding tolerance in Welsh onion. Journal of the Science of Food and Agriculture 88, 1222-1230. (SCI). 2008
9. Chen. S. D., M. C. Hsieh, M. T. Chiou, Lai Yu-Shen(賴裕順)., Cheng, Y. H, (2008). Effects of fermentation products of Ganoderma lucidum on growth performance and immunocompetence in weanling pigs. Archives of Animal Nutrition 64, 22-32. (SCI) 2008
8. Chen WJ., Lo T., Lai Yu-Shen(賴裕順)., Huang PT., Lin CC., Liao TH (2007). Construction and characterization of a bifunctional enzyme with deoxy- ribonuclease I and thioredoxin-like activities. Biochemical and Biophysical Research Communications 356, 750-755. (SCI) 2007
7. Chen WJ., Lai PJ., Lai Yu-Shen(賴裕順)., Huang PT., Lin CC., Liao TH (2007). Probing the catalytic mechanism of bovine pancreatic deoxyribonuclease I by chemical rescue. Biochemical and Biophysical Research Communications 352(3), 689-696. (SCI) 2007
6. Yu-Shen Lai(賴裕順)., John, J.A.C., Guo, I.-C., Chen, S.-C., Fang, K. and Chang, C.-Y (2003). Establishment of cell lines from grouper, Epinephelus awoara, and their susceptibility to grouper irido-and nodaviruses. Journal of Fish Diseases 26, 31-42. (SCI). 2003
5. Yu-Shen Lai(賴裕順)., John, J.A.C., Guo, I.-C., Chen, S.-C., Fang, K. and Chang, C.-Y (2002). In vitro efficiency of combined intra- and extracellular immunization of a mouse anti-YGNNV antibody gene against yellow grouper nervous necrosis virus infection. Vaccine 20,3221-3229. (SCI). 2002
4. Yu-Shen Lai(賴裕順)., S-Murali., H-C Chiu., H-Y Ju., Y-S Lin., S-C Chen., I-C Guo., K Fang and C-Y Chang (2001). Propagation of yellow grouper nervous necrosis virus in a new nodavirus-susceptible cell lines from yellow grouper, Epinephelus awoara brain tissue. Journal of Fish Diseases 24,299-309. (SCI). 2001
3. Yu-Shen Lai(賴裕順)., H-C Chiu., S-Murali., I-C Guo., S-C Chen., K Fang and C-Y Chang (2001).In vitro neutralization by monoclonal antibodies against YGNNV and immunolocalization of virus infection in yellow grouper Epinephelus awoara. Journal of Fish Diseases 24,237-244. (SCI). 2001
2. Yu-Shen Lai(賴裕順)., S-Murali., H-Y Ju., M-F Wu., I-C Guo., S-C Chen., K Fang and C-Y Chang (2000).Two iridovirus-susceptible cell lines established from kidney and liver of grouper, Epinephelus awoara, and partial characterization of grouper iridovirus. Journal of Fish Diseases 23, 379-388. (SCI). 2000
1. Yu-Shen Lai(賴裕順)., Hua-Bin Tseng., Chin-Hwa Hu. (1996).The dimerization domain of upstream binding factor contains multiple helical structure. Biochemical and Biophysical Research Communications 220, 816-823. (SCI) 1996
全部作者 論文名稱
18. 廖振偉、胡秀蓮、陳緻宇、陳宏益、賴裕順. 虹彩病毒早、中、晚期基因的抗體製備與功能分析(2012)中華民國獸醫學會暨台灣省畜牧獸醫學會PB-36
17. 林淑玟, 黃建智, 邱品文, Yu-Shen Lai(賴裕順). Identification and characterization of a putative NTPase-helicase protein homolog encoded by grouper iridovirus ORF097L. Annual Meeting Fisheries Society of Taiwan (2011)FPN-11.
15. 張雅萍、賴裕順. Development and application of scFv antibody against NNV. (2010)中華民國獸醫學會暨台灣省畜牧獸醫學會 O-033
16. 林安騏、賴裕順. Cloning and expression of canine heat shock protein 27/B1 and B3 genes. (2011)中華民國獸醫學會暨台灣省畜牧獸醫學會 PB-34
12. Yu-Hui Li, Chung-Tien Lin, Chi-Yao Chang, Yu-Shen Lai (賴裕順). Assessment of the tumorigenesis and drug susceptibility of three new canine mammary tumor cell lines.(2009)中華民國獸醫學會暨台灣省畜牧獸醫學會p-028.
13. Yen-Ling Hsiao, Yu-Shen Lai (賴裕順). Doxorubicin effect on three new establishment canine breast cancer cells. (2009)中華民國獸醫學會暨台灣省畜牧獸醫學會 p-088.
14. Chen, N-Y., Yu-Shen Lai (賴裕順), H-C. Chuang, Y-H. Ruan,Y-S. Lin, T-L. Ji and P. P. Chiou. 2009. Molecular Cloning and Characterization of Toll-like Receptor 3 in Orange-spotted Grouper (Epinephelus coioides). The 11th International Congress ISDCI 2009. Prague, Czech Republic. June 28 – July 4.
8. 曾心渝1、沈俞伶1、鄔欣妤1、賴裕順2、陳淑德2、鄭永祥2. 蛹蟲草發酵產物水萃液對巨噬細胞細胞激素之調節作用。2008台灣保健食品年會。
9. Yen-Chun Chen , Yu-Shen Lai(賴裕順). Caspase-dependent induction of apoptosis in barramundi (Lates calcarifer) muscle and swim bladder cells by grouper iridovirus (GIV) Annual Meeting Fisheries Society of Taiwan (2008).
10. I-Shu Chiu, Yen-Ling Hsiao, Jian-Jhih Huang, Wei-Jung Chen, Yeong-Hsiang Cheng, Yu-Shen Lai(賴裕順). Bupivacaine Induce Apoptosis Through Capase-dependent and Caspase-independent Pathways in Canine Breast Cancer Cell Line. (2008) 中華民國獸醫學會暨 台灣省畜牧獸醫學會- p37 .
11. Yen-Ling Hsiao, Yu-Shen Lai (賴裕順). The Analysis of Doxorubicin Resistance in Canine Breast Cancer Cells. (2008)中華民國獸醫學會暨台灣省畜牧獸醫學會.
4. Wei, Yu-Cheng, Su-Der Chen, Yu-Shen Lai(賴裕順), Yeong-Hsiang Cheng, 2007. Studies on the mechanism of Cordyceps militaris extract inducing human and canine mammary tumor cells apoptosis. 2007 Global Chinese Health Food Symposium.
5. Chen, Wei-Jung, Lai, P. J., Lai, Y. S(賴裕順)., Huang, P. T., Lin, C. C. and Liao, T. H., "Probing the catalytic mechanism of bovine pancreatic deoxyribonuclease I by chemical rescue of the active site histidine mutants." , Poster P386 in The 22nd Joint Annual Conference of Biomedical Sciences., (2007)
6. Tsai, S. C., Cheng, Y. S., Lai, Y. S(賴裕順)., Lin, Y. J., Wu, S. T., and Chen, Wei-Jung, "Differential deoxyribonucleases are involved in UV-induced apoptosis of human and canine breast cancer cell lines." , Poster P388 in The 22nd Joint Annual Conference of Biomedical Sciences., (2007)
7. Yen-Chun Chen1*, Yu-Hui Li1, Chin-Wen Chen1, I-Shu Chiu1, Pai-I Lu1, Chi-Yao Chang2, Yu-Shen Lai1(賴裕順). Establishment of two cell lines from barramundi (Lates calcarifer), and induction of apoptosis by grouper iridovirus. Program and Abstracts 2007 Annual Meeting Fisheries Society of Taiwan AO-2-4, AP-20, (2007).
2. 鄭達智、(賴裕順)、林明男、林金禜、張賜玲、陳紫媖。海鱺鰭及腦細胞株之建立及特性評估2005台灣水產學會學術論文發表會BPN-12。
3. 朱金池、邱宸子、蕭瑋依、王品蓉、(賴裕順)、張繼堯。Characterization of newly established canine mammary carcinoma cell lines and evaluation of drugs on growth inhibitory activity2005台灣生物化學及分子生物學學會-2005年宜蘭夏令營P45
1. Yu-Shen Lai (賴裕順)., John, J.A.C., Guo, I.-C., Chen, S.-C., Fang, K. and Chang, C.-Y.. In vitro efficiency of combined intra- and extracellular immunization of a mouse anti-YGNNV antibody gene against yellow grouper nervous necrosis virus infection. (2002) Institute of Zoology, Academia Sinica.